Chitosan Fibers Modified with HAp/β–TCP Nanoparticles
نویسندگان
چکیده
This paper describes a method for preparing chitosan fibers modified with hydroxyapatite (HAp), tricalcium phosphate (β-TCP), and HAp/β-TCP nanoparticles. Fiber-grade chitosan derived from the northern shrimp (Pandalus borealis) and nanoparticles of tricalcium phosphate (β-TCP) and hydroxyapatite (HAp) suspended in a diluted chitosan solution were used in the investigation. Diluted chitosan solution containing nanoparticles of Hap/β-TCP was introduced to a 5.16 wt% solution of chitosan in 3.0 wt% acetic acid. The properties of the spinning solutions were examined. Chitosan fibers modified with nanoparticles of HAp/β-TCP were characterized by a level of tenacity and calcium content one hundred times higher than that of regular chitosan fibers.
منابع مشابه
Properties of Hydrochloric Chitosan Solutions Modified With Nano-Calcium Phosphate Complex
Nature itself uses materials like cellulose to provide the structure of plants, chitin as the exoskeleton of several insects and molluscs, collagen for mechanical support in connective tissues and so on. At present, the socioeconomic situation of the modern world has raised the interest in renewable materials to use in regenerative medicine. The composition of Chitosan and/or Calcium Phosphates...
متن کاملBiodegradation Study of Microcrystalline Chitosan and Microcrystalline Chitosan/β-TCP Complex Composites
Bone repair or regeneration is a common and complicated clinical problem in orthopedic surgery. The importance of natural polymers, such as microcrystalline chitosan, and minerals such as HAp and β-TCP, has grown significantly over the last two decades due to their renewable and biodegradable source, increasing the knowledge and functionality of composites in technological and biomedical applic...
متن کاملارزیابی غلظت مواد اولیه و زمان چرخش بر روی سنتز ذرات نانوکامپوزیت β-TCP/HAp به روش رسوبگذاری
در این مطالعه، نانوکامپوزیت β-TCP/HA توسط روش رسوب شیمیایی ساخته شد. سپس تاثیر تغییر درصد وزنی و زمان چرخش بر پودر نانوکامپوزیت β-TCP/HAp بررسی شد. نمونهها توسط روشهای مختلفی مانند XRD، FTIR، میکروسکوپهای الکترونی عبوری و روبشی (TEM, FESEM)، آنالیز عنصری (EDS) و اندازهگیری اندازه ذره مشخصهیابی شدند. نتایج نشان داد که با استفاده از روش رسوب شیمیایی میتوان به نانوکامپوزیت β-HAp-TCP با اند...
متن کاملIn vitro analysis of nanoparticulate hydroxyapatite/chitosan composites as potential drug delivery platforms for the sustained release of antibiotics in the treatment of osteomyelitis.
Nanoparticulate composites of hydroxyapatite (HAp) and chitosan were synthesized by ultrasound-assisted sequential precipitation and characterized for their microstructure at the atomic scale, surface charge, drug release properties, and combined antibacterial and osteogenic response. Crystallinity of HAp nanoparticles was reduced because of the interference of the surface layers of chitosan wi...
متن کاملEffects of Adding Polysaccharides and Citric Acid into Sodium Dihydrogen Phosphate Mixing Solution on the Material Properties of Gelatin-Hybridized Calcium-Phosphate Cement
We have succeeded in improving the material properties of a chelate-setting calcium-phosphate cement (CPC), which is composed of hydroxyapatite (HAp) the surface of which has been modified with inositol hexaphosphate (IP6) by adding α-tricalcium phosphate (α-TCP) powder. In order to create a novel chelate-setting CPC with sufficient bioresorbability, gelatin particles were added into the IP6-HA...
متن کامل